Quantitative morphological analysis of features of remodeling of the synovial membrane vasculature of the temporomandibular joint in hyperglycemia

The vasulature of the synovial membrane temporomandibular joint 18 laboratory mature Vietnamese mini male pigs divided into 3 groups was morphologically studied. Group 1 – 6 control experimental animals, 2 with a 30-day’s hyperglycemia, 60-day’s hyperglycemia. Hyperglycemia induced by single intraperitoneal injection streptozotocin at dose 50 mg/kg. Pigs were sacrificed bloodletting under general thiopental sodium anesthesia 30 and 60 days after start experiment. On indicated experiment, concentration glucose in blood determined. micropreparations small caliber arteries there measured diameter vessel, lumen, thickness muscular, adventitious membranes, Wogenworth Kernogan indices; veins its vein. In arterial venous vessels, morphometry endothelial cells, their nuclei, volume damage, nuclear-cytoplasmic indices Arterial, metabolic vessels hemomicrocirculatory bed studied morphometrically, number per mm² Quantitative values processed statistically. conditions thickening tempo­romandibular joint, narrowing decrease index, an increase Wogenvoort damaged endotheliocytes, disorder revealed, outer inner diameters veins, disorders indexes, plethora noted. Structural changes hyperglycemia characterized arterioles, precapillary hemocapillaries, dilation capillary venules venules, marked microvascular density. most pronounced degree remodeling structures found